ImportError: No such file or directoryProcess Monitor revealed the secret source of the error: the Boost.Python DLL could not be found in my path. I manually copied the DLL to /usr/local/bin, and the wrapper was fine.
My conclusions are that SWIG is easier to pick up and more popular, though its popularity is declining; while Boost.Python is for those of us that pass the screening test of properly setting up Boost.Build. Although SWIG has its merits, I have decided to stick with Boost.Python.